# EPA Proposes Significant New Use Rules (SNURs) Batch 26-2

Toxic Substances Control Act (TSCA) Section 5 - Significant New Use Rules (40 CFR Part 721) U.S. Environmental Protection Agency (EPA)

Announced

Apr 24, 2026

## Description

EPA proposed Significant New Use Rules (SNURs) for chemical substances subject to premanufacture notices (PMNs) P-25-73, P-25-152, P-25-137, and P-25-151. The SNURs require 90-day notification (SNUN) to EPA before manufacturing or processing for significant new uses. EPA identified concerns for carcinogenicity, reproductive toxicity, specific target organ toxicity, and dermal/respiratory sensitization. Estimated cost per SNUN submission is $45,496.

## Sources

- Official [Significant New Use Rules on Certain Chemical Substances (26-2)](https://www.federalregister.gov/documents/2026/04/24/2026-08012/significant-new-use-rules-on-certain-chemical-substances-26-2)

## Key Findings

EPA Proposes Significant New Use Rules (SNURs) Batch 26-2